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Season 2 Episode
- Season 1 Eva Longoria, Kobe Bryant, Ellen DeGeneres
- Season 1 Jamie Foxx, Marc Anthony
- Season 1 Larry David, Kelly Osbourne
- Season 1 Charlie Sheen, Demi Lovato
- Season 1 Andy Garcia, The Real Housewives of Orange County
- Season 1 Andy Garcia, Real Housewives of OC, Justin Bieber
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- Season 1 Eva Mendes, Craig Robinson
- Season 1 Sandra Bullock, Derek Luke, Shakira
- Season 1 Laurence Fishburne, Olivia Munn
- Season 1 Taye Diggs, Kaley Kuoko, Ruben Paul
- Season 1 Laurence Fishburne , Olivia Munn, Los Lobos
- Season 1 Kathy Griffin, Rico Rodriguez
- Season 1 Hillary Duff, Scott Bakula
- Season 1 Cedric the Entertainer, Corona Girl & Morrissey
- Season 1 Hilary Duff, Scott Bakula & Rudy Moreno
- Season 1 Mariah Carey, David Beckham
- Season 1 "George Lopez" Reunion
- Season 1 David Beckham & Mariah Carey
- Season 1 Ray Romano, Lake Bell, Mariah Carey & the Cast of
- Season 1 Larry David, Lisa Lampanelli, Jay Sean, Birdman
- Season 1 Ted Danson, Bill Engvall, Orianthi
- Season 1 Jamie Foxx, Marc Anthony
- Season 1 Sandra Bullock, Derek Luke, Shakira, Chola Girl
- Season 1 Jackie Chan, Ke$ha
- Season 1 Samuel L. Jackson, Omarion
- Season 1 Charles Barkley
- Season 1 Snoop Dogg, Saoirse Ronan
- Season 1 Amber Valletta, Mark Valley
- Season 1 Brendan Fraser, Khloe and Kourtney Kardashian
- Season 1 Tyrese Gibson, Betty White
- Season 1 Samuel L, Jackson, Dianna Agron
- Season 1 Cheech and Chong, Regina King
- Season 1 Sofía Vergara, James Van Der Beek
- Season 1 Jamie Foxx and Garry Marshall
- Season 1 Topher Grace, Jewel
- Season 1 Ashton Kutcher, Emma Roberts, Carter Jenkins
- Season 1 Jennifer Garner, Hector Elizondo and Steel Magnolia
- Season 1 Season 1, Episode 45
- Season 1 Season 1, Episode 46
- Season 1 Snoop Dogg; Saoirse Ronan
- Season 1 Jennifer Lopez; Amber Valletta; Mark Valley; Christian Lander
- Season 1 Freddie Prinze Jr., Steve Austin
- Season 1 Lenny Kravitz, Khloe & Lamar Odom, Emilio Estefan
- Season 1 Ozzy Osbourne, Kendra & Hank Baskett, Alonzo Mourning
- Season 1 Shannen Doherty, Louis Psihoyos, Jessica Szohr, Jason Derulo
- Season 1 Dominic Monaghan, Kat Von D, Joe Bonamassa
- Season 1 Wanda Sykes, Peter Facinelli, Loni Love
- Season 1 Johnny Weir, Andy Garcia, Lance Gross, Lucrecia featuring Andy Garcia
- Season 1 Chris Jericho, Dakota Fanning, David Arquette, Johnny Weir, Kat Von D
- Season 1 Chris Jericho, David Arquette, Elizabeth Chavira,Trey Songz
- Season 1 Eric Andre, Eva Longoria, Sinbad
- Season 1 Chad Ochocinco, Johnny Weir
- Season 1 Annie Wersching, Foreigner, Snoop Dogg
- Season 1 Clark Duke, Ludacris
- Season 1 Johnny Sanchez, Omar Epps, Wendy Williams
- Season 1 Ron Artest, Usher
- Season 1 John Corbett, Mark Littell, Nicole Scherzinger, Steve Lyons
- Season 1 Brandy, Ray J
- Season 1 Bruno Tonioli, George Wallace, Taraji P. Henson
- Season 1 Slash, Zachary Levi
- Season 1 Chris Rock, Oscar De La Hoya, Sugar Shane Mosley
- Season 1 Audrina Patridge, Benjamin Bratt, Bryan Kellen
- Season 1 Luke Wilson, Monica
- Season 1 James Marsden, Reggie Miller
- Season 1 Kara Dioguardi, Cheech Marin & Tommy Chong, Jason Reeves
- Season 1 Angela Kinsey, Brendan Fraser, Jason Aldean
- Season 1 Chris Evans, Idris Elba, Lowell Sanders, Zoe Saldana
- Season 1 Jennifer Lopez, Ken Jeong, Ozomatli
- Season 1 Amare Stoudemire
- Season 1 Matthew Mcconaughey
- Season 1 Dallas Mavericks
- Season 1 Prince
- Season 1 Randy Jackson, Monica Potter, Paper Tongues
- Season 1 Dennis Quaid, Rampage Jackson, Rashad Evans
- Season 1 Toni Braxton
- Season 1 Sir Ben Kingsley, Janelle Monae
- Season 1 Drew Carey, Marisa Miller, Mike Posner
- Season 1 Adrien Brody, Terry Crews, Hot Chelle Rae
- Season 1 Cat Deeley, Charlie Murphy
- Season 1 Jonah Hill, Peter Frampton
- Season 1 Ashton Kucher, Hanson
- Season 1 Jackie Chan, Jaden Smith, Taraji P. Henson
- Season 1 Ice Cube, Alfre Woodard
- Season 1 Bryan Cranston, Lil Jon featuring LMFAO
- Season 1 Liam Neeson, Bradley Cooper, Sharlto Copley, Quinton "Rampage" Jackson
- Season 1 Tim Allen, Padma Lakshmi
- Season 1 Jaden Smith, Jackie Chan, Taraji P. Henson
- Season 1 Rob Schneider, Mel B, Crash Kings
- Season 1 Ozzy & Sharon Osbourne, Jillian Michaels
- Season 1 Helen Mirren, Cedric the Entertainer, Ron Artest
- Season 1 Bill Cosby, Blair Underwood, Kid 'n Play
- Season 1 100th Episode - Kobe Bryant, Louis C.K.
- Season 1 Kathy Griffin, Michael "The Situation" Sorrentino, Vinny Guadagnino, Paul "Pauly D" Delvecchio, Nicole "Snooki" Polizzi, Ronnie Margo, Samantha Giancola, Jenni "JWoww" Farley, Angelina Pivarnick
- Season 1 Kellan Lutz, Missy Peregrym, Clay Walker
- Season 1 Vivica A. Fox, Big Boi
- Season 1 Terrell Owens, Lifehouse
- Season 1 Nicolas Cage, Dania Ramirez, Shorty Rossi
- Season 1 Ali Fedotowsky, Travie McCoy & Bruno Mars
- Season 1 America Ferrera, Holly Robinson Peete, Tommy Davidson
- Season 1 Tiffani Thiessen, Enrique Iglesias
- Season 1 Selena Gomez, Wilmer Valderrama, Rob Schneider
- Season 1 Steve Carell, Maggie Q, Backstreet Boys
- Season 1 Diddy, Tony Robbins, Diddy-Dirty Money
- Season 1 Zac Efron
- Season 1 Jim Parsons, Tricia Helfer, Tom Morello & Boots Riley's band Street Sweeper Social Club
- Season 1 Luke Wilson, Margaret Cho, Billy Ray Cyrus
- Season 1 T.I., Idris Elba, Michael Ealy
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- Season 1 Eva Mendes, Josh Hutcherson, Dolph Zigler
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- Season 1 Mark Wahlberg, Bill Bellamy, David Otunga
- Season 1 Gordon Ramsay, Aubrey Plaza, R-Truth
- Season 1 Jason Statham, Aubrey Plaza, Wolfmother
- Season 1 Dylan McDermott, Kat Von D, Meat Loaf
- Season 1 Bow Wow, Lisa Edelstein, Caroline Manzo & Teresa Guidice, Twitch
- Season 1 Michelle Rodriguez, Ted Nugent
- Season 1 Justin Long, Michael Strahan, Los Lobos
- Season 1 Jason Sudeikis, Kim & Kourtney Kardashian, Korn
- Season 1 Drew Barrymore, Fantasia
- Season 1 Christina Applegate, Charlie Day, Lynyrd Skynyrd
- Season 1 Snoop Dogg, Bethenny Frankel, Goo Goo Dolls
- Season 1 Audrina Patridge, Enrique Iglesias featuring Juan Luis Guerra
- Season 1 Danny DeVito, Carmelo Anthony, La La Vasquez, Chris Spencer
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- Season 1 Michael Franti & Spearhead
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- Season 1 Kevin Connolly, Mike "The Situation" Sorrentino & Rob Schneider
- Season 1 LL Cool J., Kelly Osbourne & Santana with NAS
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- Season 1 Magic Johnson, Sara Ramirez & Far East Movement aka FM
- Season 1 Tom Bergeron & Seal
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- Season 1 Eva Longoria Parker & John Legend
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- Season 1 Bryce Dallas Howard & Criss Angel
- Season 1 Bill Maher, Lauren Conrad & Taio Cruz
- Season 1 Jon Cryer, Patti Stanger & Sean Kingston
- Season 1 Jenny McCarthy, Eric Balfour & All Star Weekend
- Season 1 Bill Maher; Lauren Conrad; Taio Cruz
Lopez Tonight - Season 1 Episode 112 Zac Efron
4.75 60 minutes 
