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Season
- Season 1 1993-08-30
- Season 2 1994-08-29
- Season 3 1995-09-04
- Season 4 1996-09-02
- Season 5 1997-09-01
- Season 6 1998-08-31
- Season 7 1999-09-07
- Season 8 2000-08-21
- Season 9 2001-08-20
- Season 10 2002-09-03
- Season 11 2003-09-01
- Season 12 2004-08-23
- Season 13 2005-08-29
- Season 14 2006-08-28
- Season 15 2007-09-04
- Season 16 2008-09-02
- Season 17 2009-08-31
- Season 18 2011-01-03
- Season 19 2012-01-03
- Season 20 2013-01-02
- Season 21 2014-01-06
- Season 22 2014-09-02
Season 22 Episode
- Season 19 Will Arnett, Lisa Lampanelli, Guided by Voices
- Season 19 Brian Williams, WU LYF
- Season 19 Tina Fey, Jeremy Irvine, Barr Brothers
- Season 19 Kristen Bell, Dan Naturman, Blind Pilot
- Season 19 Mark Wahlberg, Heather Morris, Snow Patrol
- Season 19 Kate Beckinsale, Marv Albert, The Little Willies
- Season 19 Dolly Parton, Alan Zweibel
- Season 19 Sen. John McCain, Johnny Winter
- Season 19 Viggo Mortensen, Dennis Regan, Tony Bennett
- Season 19 Simon Baker, Elizabeth Banks, Seal
- Season 19 Ricky Gervais, Jessica Chastain, Kathleen Edwards
- Season 19 Marg Helgenberger, Michael Fassbender, Ellie Goulding
- Season 19 Kathy Griffin, Simon Helberg, Joseph Arthur
- Season 19 Dana Carvey, Jon Fisch, Los Campesinos!
- Season 19 Jennifer Lopez, Rob Schneider, James McCartney
- Season 19 Bill Murray, Girls' Generation
- Season 19 Howard Stern, The Airborne Toxic Event
- Season 19 Woody Harrelson, Stephen Merchant, Lana Del Rey
- Season 19 Michelle Williams, Jake Johannsen, Ziggy Marley
- Season 19 Eli Manning, Sarah Michelle Gellar, Die Antwoord
- Season 19 Denzel Washington, The Fray
- Season 19 Ryan Reynolds, Ellie Kemper, Dierks Bentley
- Season 19 Nicolas Cage, Michelle Dockery, The Kills
- Season 19 David Spade, Betty Wright
- Season 19 Reese Witherspoon, Michael Weatherly, Top Ten by Sports Illustrated Swimsuit models, Kasabian
- Season 19 Viola Davis, the 2012 Sports Illustrated Swimsuit cover model, Mark Ronson, Erykah Badu, The Dap-Kings, Zigaboo Modeliste
- Season 19 Jon Stewart, American Bagging Champion Stephanie Teteak, Yelawolf with Kid Rock
- Season 19 Joan Rivers, Andrew Lincoln, Jason Mraz
- Season 19 Kristen Wiig, Mike Birbiglia, Butch Walker and the Black Widows
- Season 19 Jack Hanna, Jesse Tyler Ferguson
- Season 19 Alec Baldwin, Eric Hutchinson
- Season 19 Paul Rudd, John Witherspoon, Heartless Bastards
- Season 19 Kristin Chenoweth, Joe Scarborough, K'naan featuring Nelly Furtado
- Season 19 Matthew Broderick, Nick Griffin, We Are Augustines
- Season 19 Ed Helms, Dan Patrick, Lyle Lovett
- Season 19 Nathan Lane, Pauley Perrette, Estelle
- Season 19 Neil Patrick Harris, Taylor Kitsch, Robert Glasper Experiment featuring Lupe Fiasco & Bilal
- Season 19 Jon Hamm, Ted Alexandro, White Rabbits
- Season 19 Will Ferrell, Jon Bernthal
- Season 19 Amanda Peet, Nick Offerman, Top Ten by Cee-Lo Green, The Chieftains with the Low Anthem
- Season 19 Martin Short, The Ting Tings
- Season 19 Michelle Obama, Esperanza Spalding
- Season 19 Jennifer Lawrence, Gail Collins, The Shins
- Season 19 Debra Messing, Josh Hutcherson, Oberhofer
- Season 19 Rachel Maddow, Timothy Olyphant, Train
- Season 19 Jason Sudeikis, Lionel Richie, Jason Aldean
- Season 19 Chris Elliott, Mohamed Nasheed, Justin Townes Earle
- Season 19 Tracy Morgan, Jim Rome, The Broadway musical 'Once'
- Season 19 Megan Mullally, Joe Wong, Band of Skulls
- Season 19 Keith Olbermann, Allison Williams, Lukas Nelson & Promise of the Real
- Season 19 Kiefer Sutherland, Eugene Levy, The Punch Brothers
- Season 19 Ricky Gervais, Cobie Smulders, Tennis
- Season 19 Sean Hayes, Shooter Jennings
- Season 19 Magic Johnson, Larry Bird, Jim Gaffigan, Kaiser Chiefs
- Season 19 Billy Crystal, Alabama Shakes
- Season 19 Julia Louis-Dreyfus, Keith Alberstadt, Bonnie Raitt
- Season 19 Jason Segel, Zach Wahls, Fun
- Season 19 Amy Poehler, Wendy Williams, Trampled by Turtles
- Season 19 Rob Lowe, Gov. Brian Schweitzer, The War on Drugs
- Season 19 Robin Williams, Andrew Luck
- Season 19 Madden NFL 13 Cover Calvin Johnson, Chris Hemsworth, Darrell Hammond, Miike Snow
- Season 19 Don Rickles, Carrie Underwood
- Season 19 Seth Meyers, Krysten Ritter, Father John Misty
- Season 19 Stupid Pet Tricks, Johnny Galecki, Norah Jones
- Season 19 Stephen Colbert, Chloe Grace Moretz, The cast of 'Nice Work If You Can Get It'
- Season 19 Anderson Cooper, Yves Rossy, Electric Guest
- Season 19 Dr. Phil McGraw, Beth Behrs, Spiritualized
- Season 19 Jim Parsons, Mika Brzezinski, Macy Gray
- Season 19 Eva Longoria, Tom Dreesen, Florence and The Machine
- Season 19 Kid Scientists, Elizabeth Banks, Edward Sharpe & The Magnetic Zeros
- Season 19 Jon Cryer, Tommy Johnagin, M. Ward
- Season 19 Kelly Ripa, Adam Scott, Tenacious D
- Season 19 Brian Williams, El-P
- Season 19 Betty White, Moses Maddox, Best Coast
- Season 19 Conan O'Brien, Regina Spektor, John Mayer
- Season 19 Sacha Baron Cohen, Julie Chen, Beach House
- Season 19 Lea Michele, Barry Sonnenfeld, Shaolin Warriors of Ringling Bros
- Season 19 Will Smith, Gossip
- Season 19 Piedmont Bird Callers, Bill O'Reilly, Pitbull
- Season 19 Joan Rivers, Dario Franchitti, Silversun Pickups
- Season 19 Neil Patrick Harris, Noomi Rapace, Alan Jackson
- Season 19 Jane Fonda, Mayor of London Boris Johnson, Jimmy Cliff
- Season 19 Bill Murray, The Temper Trap
- Season 19 Mark Wahlberg, Sebastian Vettel, Black Box Revelation
- Season 19 Jack Hanna, Patti Smith
- Season 19 Adam Sandler, Jerry Douglas
- Season 19 Regis Philbin, Lenny Marcus, Elizabeth Cook
- Season 19 Denis Leary, Olivia Wilde, The Pierces
- Season 19 Jeff Daniels, Benjamin Walker, Walk the Moon
- Season 19 Alec Baldwin, Michael Kiwanuka
- Season 19 Justin Bieber, Michael Ian Black
- Season 19 Emma Stone, Jimmie Walker, Diamond Rugs
- Season 19 LeBron James, Andrew Garfield, Maroon 5
- Season 19 Channing Tatum, Scott Pelley, The Gaslight Anthem
- Season 19 Blake Lively, Drew Brees
- Season 19 Ray Romano, Tom Waits, Top Ten by American League All-Stars
- Season 19 Queen Latifah, Fred Armisen, Cory Chisel and the Wandering Sons
- Season 19 Bryan Cranston, R.A. Dickey, Zac Brown Band
- Season 19 Anne Hathaway, Moody McCarthy, Loudon Wainwright III
- Season 19 Morgan Freeman, Gallagher, Nas
- Season 19 Roseanne Barr, Aubrey Plaza, Jeff the Brotherhood
- Season 19 Kyra Sedgwick, Mike Golic and Greenberg, Red Wanting Blue
- Season 19 Woody Harrelson, Todd Barry, Grafitti6
- Season 19 Will Ferrell, Rufus Wainwright
- Season 19 Zach Galifianakis, Former U.S. Army Sgt. Valerie Brown, Allen Stone
- Season 19 Jonah Hill, Dr. Leonard Girardi, Milo Greene
- Season 19 Joel McHale, Andrew Norelli, Will.I.Am
- Season 19 Andy Samberg, Ashton Eaton, Glen Hansard
- Season 19 Jennifer Garner, The U.S. Women's Olympic Gymnastics team, Rodriguez
- Season 19 Tom Brokaw, Dana Vollmer, Beth Orton
- Season 19 Tracy Morgan, Erik Kynard, Ben Howard
- Season 19 Kelsey Grammer, Olivia Munn, Train
- Season 19 Bill Hader, Mary-Louise Parker, The Walkmen
- Season 19 Rachel Maddow, Serena Williams, Elle King
- Season 19 Kathy Griffin, Michael Somerville, Josh Turner
- Season 19 Jake Gyllenhaal, Sharon Osbourne, Neon Trees
- Season 19 Amy Adams, Paul Teutul Sr. & Paul Teutul Jr., Hacienda
- Season 19 Michelle Obama, The Chevin
- Season 19 Bruce Willis, Brian Regan, The Heavy
- Season 19 Claire Danes, Dwyane Wade, Bob Mould
- Season 19 Emma Watson, Julie Chen, Matchbox Twenty
- Season 19 Howard Stern, Jason Aldean
- Season 19 Joseph Gordon Levitt, Mindy Kaling, Of Gentlemen and Cowards
- Season 19 President Barack Obama
- Season 19 Michael Strahan, Arthur Meyer
- Season 19 Nathan Lane, Ryan Hunter-Reay, The Killers
- Season 19 Steve Martin, Gotye
- Season 19 Stupid Human Tricks, Kaley Cuoco, The Whigs
- Season 19 David Cameron, Jonny Lee Miller
- Season 19 Jimmy Fallon, Neil Young, Lupe Fiasco
- Season 19 Regis Philbin, Tom Dreesen, Dwight Yoakam
- Season 19 Stephen Colbert, Theresa Caputo, Martha Wash
- Season 19 Martin Short, Kat Dennings
- Season 19 Tina Fey, Rick Santorum, LP
- Season 19 Craig Ferguson, Anna Kendrick, The Raveonettes
- Season 19 Billy Crystal, The Wallflowers
- Season 19 Jack Hanna, Max Greenfield
- Season 19 Kevin James, Chris Elliott, Miguel
- Season 19 Salma Hayek Pinault, Nick Offerman, KISS
- Season 19 Lucy Liu; Rob Corddry; Daughter
- Season 19 John Goodman, Jeff Altman, Jamey Johnson with Alison Krauss
- Season 19 Tom Hanks; Tony Bennett
- Season 19 Taylor Swift; Rachel Maddow
- Season 19 Bill O'Reilly; Nicole Snooki Polizzi; The Lumineers
- Season 19 Donald Trump; Adam Levine; Carly Rae Jepsen
- Season 19 Dennis Quaid; Krysten Ritter; Diamond Rings
- Season 19 Denzel Washington, Paul Banks
- Season 19 Jim Cantore; Ken Burns; Andrew Bird
- Season 19 Katie Couric; Rita Ora
- Season 19 Steven Tyler and Joe Perry; Judy Greer; Aerosmith
- Season 19 Jason Sudeikis; Michael Che; Ultraĩsta
- Season 19 Ricky Gervais; Simon Helberg; Ty Segall
- Season 19 Brian Williams; Ne-Yo
- Season 19 Robin Williams; Lianne La Havas
- Season 19 Anderson Cooper; Myq Kaplan; Alberta Cross
- Season 19 Bradley Cooper; Robert Klein; Soundgarden
- Season 19 Julianna Margulies; Mumford & Sons
- Season 19 Alec Baldwin; Dirty Projectors
- Season 19 Zooey Deschanel; Lisa Lampanelli; Donald Fagen
- Season 19 Dr. Phil McGraw; Carmen Lynch; Divine Fits
- Season 19 Jessica Biel; Pete Townshend; Philip Phillips
- Season 19 Amy Poehler; Josh Hutcherson; Tegan and Sara
- Season 19 Scarlett Johansson; Willie Nelson; Gary Clark Jr.
- Season 19 Led Zeppelin; John Krasinski; Paloma Faith
- Season 19 Matt Damon; Martin Freeman; JD McPherson
- Season 19 Albert Brooks; Diana Krall
- Season 19 Bill Murray; Vintage Trouble
- Season 19 Dustin Hoffman; One Direction
- Season 19 Anne Hathaway; Jake Johnson; “The President's Own” United States Marine Band
- Season 19 Amanda Seyfried; Natalia Makarova; Awolnation
- Season 19 Billy Crystal; James Balong; Grizzly Bear
- Season 19 Jamie Foxx; Julie Chen; DIIV
- Season 19 Samuel L. Jackson; Carrie Brownstein & Fred Armisen; Jason Isbell and the 400 Unit
- Season 19 Tom Cruise; MNDR
- Season 19 Paul Rudd; Alicia Keys
- Season 19 Seth Rogen; John Witherspoon
- Season 19 Katie Holmes; Jon Bon Jovi
- Season 19 Naomi Watts; Jay Thomas; Darlene Love
Late Show with David Letterman - Season 19 Episode 75 Conan O'Brien, Regina Spektor, John Mayer
6.26 63 minutes Dave welcomes late night talk show host Conan O'Brien, musical guest Regina Spektor, and musician John Mayer sits in with Paul Shaffer & the CBS Orchestra.
Conan O'Brien tells Dave about the differences between himself and Jay Leno. Conan O'Brien tells what happened when his son had a hunger fit before meeting President Obama.
